mTORシグナル伝達のトランスレーション環境は,がんの発症と転移を誘導する

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Updated: May 24, 2026

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
07:38

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

Published on: June 6, 2025

Andrew C Hsieh1, Yi Liu, Merritt P Edlind

  • 1School of Medicine and Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, USA.

Nature
|February 28, 2012
PubMed
まとめ

腫瘍性mTORシグナリングは,前立腺がん遺伝子の特異的な翻訳を駆動し,転移を促進します. INK128という新しいmTOR阻害剤は,このシグネチャーを効果的に再プログラムし,不治の前立腺がんの転移に治療的可能性を秘めています.

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