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Updated: May 24, 2026

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer
08:29

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

Published on: November 1, 2019

SUMO-改変PCNAの認識には,Srs2のタンデム受容体モチーフが必要です

Anthony A Armstrong1, Firaz Mohideen, Christopher D Lima

  • 1Structural Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.

Nature
|March 3, 2012
PubMed
まとめ

ウビキチン (Ub) とSUMO (Smt3) は,細胞シグナル伝達のためのタンパク質を修正する. 研究者らは,Srs2ヘリカーゼは,SUMO-改変PCNAを特定的に認識するために2つのモチーフを使用しており,これはDNA修復経路にとって極めて重要です.

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