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中国における慢性腎疾患の流行:横断的な調査
Luxia Zhang1, Fang Wang, Li Wang
1Peking University Institute of Nephrology, Division of Nephrology, Peking University First Hospital, Beijing, China.
Lancet (London, England)
|March 6, 2012
まとめ
慢性腎臓病は,中国の成人の10%以上,合計約1億2000万人に罹患しています. この全国調査は,経済的に発展している農村地域や特定の地域において,標的を絞った介入の緊急の必要性を強調しています.
科学分野:
- ネフロロジーはネフロロジーを用います.
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- 慢性腎臓病 (CKD) の罹患率は,世界的に,特に発展途上国において高い.
- 中国では,推定グルメルフィルタレーション率 (eGFR) とアルブミヌリアの両方を用いてCKDを評価する包括的な全国調査が欠けていました.
- この研究は,中国の経済的な多様性を考慮して,全国的なCKDの流行率評価の必要性に対処しています.
研究 の 目的:
- 中国における慢性腎臓病 (CKD) の全国的な罹患率を決定する.
- 推定グルメルフィルタレーション率 (eGFR) とアルブミヌリアを用いて,CKDに関連した要因を特定する.
- 中国におけるCKD患者の総数を推定する.
主な方法:
- 中国人成人の47,204人を対象とした全国的な横断調査.
- eGFR <60 mL/min/1.73 m2またはアルバミヌリアの存在によって定義されるCKD.
- アンケート,物理的な測定,検査 (血清のクレアチニン,尿のアルバミン/クレアチニン) で収集されたデータ.
主要な成果:
- CKDの調整された罹患率は10.8%で,推定1億1950万人の成人に相当する.
- 低GFRの罹患率は1.7%で,アルバミヌリアの罹患率は9.4%でした.
- 北部と南西部の地域では,より高いCKDの流行が観察され,農村部ではアルブミヌーリアに関連した経済発展. 関連因子には,年齢,高血圧,糖尿病,心血管疾患歴などがあります.
結論:
- 慢性腎臓病は,中国における重大な公衆衛生上の課題である.
- ターゲットを絞った介入は,経済的に発展している農村地域や特定の地理的地域の住民にとって極めて重要です.
- この結果は,全国的に包括的なCKDスクリーニングと管理戦略の重要性を強調しています.
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