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Updated: May 24, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
11:19

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 25, 2011

リボソーム内のtmRNAとSmpBによってコドンがない場合の解読

Cajetan Neubauer1, Reynald Gillet, Ann C Kelley

  • 1Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, UK.

Science (New York, N.Y.)
|March 17, 2012
PubMed
まとめ

バクテリアの停滞したリボソームは,転送メッセンジャーRNA (tmRNA) とSmpBタンパク質によって救出されます. 結晶構造は,SmpBがtRNAとmRNAをどのように模倣し,正常な翻訳を妨げることなく救助を容易にすることを明らかにしています.

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