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ルシル-tRNA合成酵素は,mTORC1シグナル伝達経路のための細胞内ルシンのセンサーです

Jung Min Han1, Seung Jae Jeong, Min Chul Park

  • 1Medicinal Bioconvergence Research Center, Seoul National University, Seoul 151-742, Republic of Korea.

Cell
|March 20, 2012
PubMed
まとめ

ルシル-tRNA合成酵素 (LRS) は,mTORC1経路のアミノ酸センサとして作用する. LRSはRag GTPaseを直接活性化し,アミノ酸誘発mTORC1シグナリングを媒介する.

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