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Updated: May 7, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Published on: October 26, 2015

AAA+ATPアゼモーターの小分子阻害剤であるサイトプラズミックダイネイン

Ari J Firestone1, Joshua S Weinger, Maria Maldonado

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|March 20, 2012
PubMed
まとめ

研究者らは,サイトプラズマのダイネイン (モータータンパク質) の最初の特定の小分子対抗体であるシリオブレビンを発見した. これらの化合物は,ダイネインによって調節される細胞過程を混乱させ,生物学的研究のための新しいツールを提供します.

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