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Anti-Shine-Dalgarno配列は,バクテリアの翻訳停止とコドン選択を誘導する

Gene-Wei Li1, Eugene Oh, Jonathan S Weissman

  • 1Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, California 94158, USA.

Nature
|March 30, 2012
PubMed
まとめ

バクテリアの翻訳速度は,希少な転送RNAではなく,コード領域内のシャイン-ダルガーノ (SD) 配列によって驚くほど影響を受けます. この発見は,内部的なSDのような配列が,タンパク質合成速度に影響することによって,ゲノム進化をどのように駆動するかを明らかにしています.

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