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Updated: May 5, 2026

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規制解除されたMYC発現はAMPK関連キナーゼ5への依存を誘発する

Lidan Liu1, Jannes Ulbrich, Judith Müller

  • 1Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

Nature
|March 31, 2012
PubMed
まとめ

AMPK関連キナーゼ5 (ARK5) を標的にすることは,MYC駆動がんに対する新しい治療戦略を提供します. ARK5を阻害すると,代謝性ホメオスタシスが乱され,がん細胞死亡とマウスモデルでの生存期間が延長されます.

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