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中国人男性と女性の血清脂質と脂質タンパク質
Wenying Yang1, Jianzhong Xiao, Zhaojun Yang
1Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China. ywy_1010@yahoo.com.cn
Circulation
|April 12, 2012
まとめ
高血清コレステロールレベルは中国で一般的です.
科学分野:
- 心血管疾患の流行病学について
- 脂質代謝の研究について
- 中国における公衆衛生
背景:
- 心血管疾患は,中国で主要な死因であり,生活習慣の変化に関連しています.
- 血清脂質と脂質タンパク質のレベルを推定することは,公衆衛生にとって極めて重要です.
- 脂質プロファイルの理解は,心血管疾患の予防戦略を伝える.
研究 の 目的:
- 中国の成人の集団における血清脂質と脂質タンパク質の全国的流行を決定する.
- 中国全土のコレステロールとトリグリセリドのレベルに関する最新データを提供するためです.
- 高コレステロールの認識,治療,制御の現状を評価する.
主な方法:
- 中国人成人の46,239人 (年齢20歳以上) の全国的に代表的なサンプルを対象に,横断的な研究が行われました.
- 断食中の血清総コレステロール,高密度脂質タンパク質コレステロール,低密度脂質タンパク質コレステロール,トリグリセリドを測定した.
- 年齢基準の推定値と人口の割合を計算した.
主要な成果:
- 血清総コレステロールの平均値は4.72 mmol/Lであり,9.0%が高コレステロール (≥6.22 mmol/L) であった.
- 平均低密度の脂質タンパク質コレステロールは2.68 mmol/Lであり,3.0%が非常に高いレベル (≥4.92 mmol/L) であった.
- 22.3%が低高密度脂質タンパク質コレステロール (<1.04 mmol/L) を有しており,高コレステロールの認識/治療/コントロールは低い (11.0%/5.1%/2.8%).
結論:
- 血清総コレステロールと低密度の脂質タンパク質コレステロールのレベルは高く,中国では増加しています.
- ディスリピデミアの認知度,治療,制御率が低いことは,公衆衛生上の大きな課題となっています.
- 効果的な介入がなければ,動脈硬化性心血管疾患は実質的に増加すると予測されています.
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