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Updated: May 5, 2026

Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies
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Hsp72は筋肉機能を保ち,重度の筋縮の進行を遅らせます

Stefan M Gehrig1, Chris van der Poel, Timothy A Sayer

  • 1Basic and Clinical Myology Laboratory, Department of Physiology, University of Melbourne, Victoria, 3010, Australia.

Nature
|April 13, 2012
PubMed
まとめ

BGP-15で熱ショックタンパク質72 (Hsp72) の発現を増加させることで,筋肉機能が改善され,デュシェンヌ筋縮症 (DMD) のマウスモデルにおける病理が軽減されます. このアプローチは,DMDおよび同様の筋肉消耗状態の治療に有望であることが示されています.

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