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Updated: May 23, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

チオール-エネ化学を用いたイソペプチド結合の鍛錬:イソペプチダゼの活性の研究のために,サイト特有のユビキチン分子結合

Ellen M Valkevich1, Robert G Guenette, Nicholas A Sanchez

  • 1Department of Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin 53706-1322, USA.

Journal of the American Chemical Society
|April 14, 2012
PubMed
まとめ

チオール-エネ結合 (TEC) 化学は,枝分かれしたユビキチントリマーの作成を可能にします. この方法により,研究者は,ユビキチンの配置がデウビキチナース活性にどのように影響するかについて研究することができ,タンパク質の調節に関する新しい洞察を明らかにすることができます.

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Detection of Protein Ubiquitination Sites by Peptide Enrichment and Mass Spectrometry11:54

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