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Updated: May 23, 2026

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
11:50

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

ゲノム全体の表遺伝子記号と転写制御のダイナミックな変換により,T細胞の同一性を確立する

Jingli A Zhang1, Ali Mortazavi, Brian A Williams

  • 1Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

Cell
|April 17, 2012
PubMed
まとめ

この研究は,転写因子GATA-3とPU.1が,遺伝子発現と表遺伝的マークを調節することによって,T細胞の発達をどのように制御するかを明らかにしています. それは,T細胞のコミットメント中に遺伝子の活性化と抑制のダイナミックなメカニズムを明らかにします.

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Chromatin Immunoprecipitation (ChIP) in Mouse T-cell Lines11:39

Chromatin Immunoprecipitation (ChIP) in Mouse T-cell Lines

Published on: June 17, 2017

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