フォーマルデヒドによる[FeFe]-ヒドロゲネーゼの抑制と,バイオヒドロゲン活性化に対するより広範なメカニズム的意味合い

Carina E Foster1, Tobias Krämer, Annemarie F Wait

  • 1Department of Chemistry, Inorganic Chemistry Laboratory, University of Oxford, South Parks Road, Oxford, OX1 3QR, United Kingdom.

まとめ

フォーマルデヒドは[FeFe]-ヒドロゲネーゼの可逆性阻害剤であり,還元状態に結合する. この研究では,ホルムアルデヒドが,触媒サイクルにおける反応性Fe-hydrido中間物質を標的としていることが明らかになりました.

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