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Updated: May 23, 2026

4D Imaging of Protein Aggregation in Live Cells
08:59

4D Imaging of Protein Aggregation in Live Cells

Published on: April 5, 2013

タンパク質の折りたたみと結合における中間状態の構造

Philipp Neudecker1, Paul Robustelli, Andrea Cavalli

  • 1Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Science (New York, N.Y.)
|April 21, 2012
PubMed
まとめ

タンパク質の誤折り付く中間物質は,神経変性疾患におけるアミロイド線維の形成を開始する可能性があります. この研究は,重要な中間物質の構造を明らかにし,露出地域が集積をいかに推進するかを示しています.

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