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Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

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関連する実験動画

Updated: May 22, 2026

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types
09:31

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types

Published on: May 10, 2016

レーザーでスパインドルアーキテクチャを剖析する.

Pierre Recouvreux1, Marileen Dogterom

  • 1FOM Institute AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands.

Cell
|May 1, 2012
PubMed
まとめ
この要約は機械生成です。

研究者は,レーザーアブレーションを用いて脊椎動物のメオティック・スピンドルを定量的に特徴付け,その組立メカニズムを明らかにした. この画期的な発見は,密度の高い微小管の構造に対する光顕微鏡の限界を克服しています.

科学分野:

  • 細胞生物学 細胞生物学
  • バイオフィジックス 生物物理学

背景:

  • スピンドル内のマイクロチューブルは密集しており,従来の光顕微鏡と超解像度の光顕微鏡で視覚化することを妨げています.
  • スピンドル構造を理解することは,細胞分裂と発達生物学にとって極めて重要です.

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Isotropic Light-Sheet Microscopy and Automated Cell Lineage Analyses to Catalogue Caenorhabditis elegans Embryogenesis with Subcellular Resolution
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関連する実験動画

Last Updated: May 22, 2026

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types
09:31

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types

Published on: May 10, 2016

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Isotropic Light-Sheet Microscopy and Automated Cell Lineage Analyses to Catalogue Caenorhabditis elegans Embryogenesis with Subcellular Resolution

Published on: June 6, 2019

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Laser Microdissection for Species-Agnostic Single-Tissue Applications

Published on: March 31, 2022