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関連する概念動画

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Hepatic Encephalopathy01:29

Hepatic Encephalopathy

DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic shunting—including...

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Updated: May 22, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

E型肝炎 (E型肝炎) について

Nassim Kamar1, Richard Bendall2, Florence Legrand-Abravanel3

  • 1Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France; Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France; Université Paul Sabatier, Toulouse, France.

Lancet (London, England)
|May 3, 2012
PubMed
まとめ
この要約は機械生成です。

世界的に急性ウイルス性肝炎の一般的な原因であるE型肝炎ウイルス (HEV) は,1980年代に発見されました. 最近の調査結果によると,HEVは先進国にも存在しており,世界の健康への影響に関する理解が変わりつつあります.

さらに関連する動画

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

関連する実験動画

Last Updated: May 22, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

科学分野:

  • * ウイルス学と疫学
  • * 感染症
  • *公衆衛生について

背景:

  • * E型肝炎ウイルス (HEV) は,1980年代のソビエト連邦によるアフガニスタン占領中に発生し,当初は軍事収容所で発生した肝炎の発生により確認された.
  • * ウイルスは,感染した兵士の便を摂取した研究者の電子顕微鏡で検出されました.
  • *HEVは,現在,世界的に急性ウイルス性肝炎の主要な原因として認識されており,特に資源が乏しい地域で流行しています.

研究 の 目的:

  • * E型肝炎ウイルス (HEV) に関する最近の科学的発見を紹介する.
  • *新しい発見が,HEVが人間の健康に及ぼす影響に関する世界的な理解をどのように形づくったかを明らかにする.
  • * HEVの流行病学の進化を強調し,先進国におけるその存在を含む.

主な方法:

  • * 科学文献のレビューと,HEVに関する最近の研究成果.
  • * HEV感染に関連する疫学データと臨床報告の分析.
  • * HEVの検出,感染,疾病負担に関する情報の統合.

主要な成果:

  • * HEVは当初,特定の流行地域に限定されていると考えられていた.
  • *最近の研究は,先進国におけるHEVの存在と重要性を確認しています.
  • *HEVの世界的な健康への影響は,これまで考えられていたよりも広範囲に広がっています.

結論:

  • *E型肝炎は,世界中に広まっており,重要な世界的な健康問題です.
  • * HEVの地理的分布と影響は,当初認識されていたよりも広い.
  • * 世界的にHEVの影響を管理・軽減するには,継続的な研究が不可欠です.