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Induction of Petite Colonies in Candida glabrate via Rose Bengal-Mediated Photodynamic Therapy
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カンジダ・アルビカンスのチアミンピリミジン生物合成:ヒスティジンとピリドクサールリン酸塩の驚くべき反応

Rung-Yi Lai1, Siyu Huang, Michael K Fenwick

  • 1Department of Chemistry, Texas A&M University, College Station, 77843, United States.

Journal of the American Chemical Society
|May 10, 2012
PubMed
まとめ

この研究では,ヒスティジンは,ピリドクサルリン酸塩 (PLP) と新しい酵素経路を用いて,カンジダ・アルビカンスのピリミジン形成の源として特定されています. ピリミジン合成酵素は単一ターンオーバー酵素として機能し,ユニークな生化学的プロセスを明らかにします.

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