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m6A-seqqによって明らかにされたヒトとマウスのm6ARNAメチロームのトポロジー

Dan Dominissini1, Sharon Moshitch-Moshkovitz, Schraga Schwartz

  • 1Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel.

Nature
|May 12, 2012
PubMed
まとめ

研究者は,ヒトとマウスのトランスクリプトーム全体にN(6) -メチラデノシン (m(6) A) RNAの改変をマッピングしました. この広範囲にわたる改変は,遺伝子発現の調節と代替スプライシングにおいて重要な役割を果たします.

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