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Updated: May 5, 2026

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms
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Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms

Published on: July 7, 2011

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ウヴォモルリンの1つのCa2+結合部位における単一のアミノ酸の置換により,粘着機能は廃止されます

M Ozawa1, J Engel, R Kemler

  • 1Max-Planck Institut für Immunobiologie, Molekulare Embryologie, Freiburg, Federal Republic of Germany.

Cell
|November 30, 1990
PubMed
まとめ

合成ペプチドと突然変異のウボモルリンは,カルシウム (Ca2+) の結合が細胞粘着に不可欠であることを示しています. 単一のアスパルチン酸を交換すると,この結合が破壊され,分子の粘着機能が廃止されます.

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