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Updated: May 22, 2026

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
11:10

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation

Published on: July 6, 2022

FMRPによるNOS1の種別依存の転写後の調節が,発達中の脳皮質で行われる

Kenneth Y Kwan1, Mandy M S Lam, Matthew B Johnson

  • 1Department of Neurobiology and Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA.

Cell
|May 15, 2012
PubMed
まとめ

脆いX症候群 (FXS) は,FMRPタンパク質の損失を伴い,知的障害に影響を及ぼします. この研究は,FMRPが発達中の人間の脳におけるNOS1タンパク質の翻訳を調節し,認知機能に不可欠であることを明らかにしています.

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Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models

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Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation10:29

Inducing Cre-lox Recombination in Mouse Cerebral Cortex Through In Utero Electroporation

Published on: November 17, 2017

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