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Updated: Jan 11, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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ナルトリンドールと結合する δ-オピオイド受容体の構造

Sébastien Granier1, Aashish Manglik, Andrew C Kruse

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA. granier@stanford.edu

Nature
|May 19, 2012
PubMed
まとめ

マウスデルタオピオイド受容体 (δ-OR) の結晶構造は,その結合ポケットに保存されたおよび異なる領域を明らかにします. この発見は,オピオイド受容体がリンガンド選択性を達成する方法を説明し,メッセージアドレスモデルを検証しています.

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