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Updated: May 22, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
08:15

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

21の乳がんのゲノムを形作る突然変異プロセス

Serena Nik-Zainal1, Ludmil B Alexandrov, David C Wedge

  • 1Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.

Cell
|May 22, 2012
PubMed
まとめ

癌ゲノムは,DNAの損傷と修復による変異パターンを明らかにします. 研究者らは,BRCA1/BRCA2変異を含む乳がんの異なる変異シグネチャを特定し,kataegisと呼ばれる局所的な超変異を観察しました.

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Transmitochondrial Cybrid Generation Using Cancer Cell Lines

Published on: March 17, 2023

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