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Updated: May 22, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

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酵素触媒による量子トンネリング現象に対する圧力効果は,タンパク質特有の構造的,動的変化から生じる

Sam Hay1, Linus O Johannissen, Parvinder Hothi

  • 1Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK. sam.hay@manchester.ac.uk

Journal of the American Chemical Society
|May 29, 2012
PubMed
まとめ

酵素触媒に及ぼす圧力と温度の影響は複雑である. 原子学的シミュレーションにより,圧力に依存する動性同位体効果は,酵素反応における量子トンネリングを決定的に証明するものではないことが明らかになった.

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