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Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments
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Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments

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遠端軸索細胞骨格は軸索内境界を形成し,軸索の初期セグメントアセンブリを制御する

Mauricio R Galiano1, Smita Jha, Tammy Szu-Yu Ho

  • 1Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.

Cell
|May 29, 2012
PubMed
まとめ

アンキリンB (ankB) とスペクトリンで構成される遠軸細胞骨格は境界線として作用する. この境界線は,アンキリンG (ankG) を軸索初期セグメント (AIS) に制限し,ニューロンの極性と適切なチャネルクラスタリングを確保します.

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