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Updated: May 21, 2026

Evaluation of Synaptic Multiplicity Using Whole-cell Patch-clamp Electrophysiology
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α2δ表現は,シナプス前カルシウムチャネルの豊富さと放出確率をセットします

Michael B Hoppa1, Beatrice Lana, Wojciech Margas

  • 1Department of Biochemistry, Weill Cornell Medical College, New York, New York 10023, USA.

Nature
|June 9, 2012
PubMed
まとめ

この研究では,α2delta (α2δ) サブユニットがシナプス電圧誘導カルシウムチャネル (VGCC) のレベルと機能を調節することを明らかにしました. これらのサブユニットは,シナプスで効率的なカルシウム (Ca2+) 流入とエクソサイトーシスを可能にすることで,神経伝達物質の放出確率を高めます.

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