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Updated: May 21, 2026

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
12:26

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

Published on: February 12, 2022

トリガーファクターは,動的トラッピングを通じて共同翻訳的折り畳みを遅らせ,同時に,新生鎖を異常な細胞相互作用からステリカルに保護します

Edward P O'Brien1, John Christodoulou, Michele Vendruscolo

  • 1Department of Chemistry, University of Cambridge, Cambridge, UK.

Journal of the American Chemical Society
|June 12, 2012
PubMed
まとめ

E. coli のトリガーファクター (TF) チャペロンは,小さなタンパク質の折り畳みを変化させないが,より大きなタンパク質を運動的に捕まえて遅らせる. これは,再編成率の減少,トンネルの長さの増加,鎖の絡み合いによって起こります.

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