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Updated: May 21, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

マルチサブユニットタンパク質の運動的にアクセス可能なトンネルを通るガス拡散の効果的なシミュレーション:T状態のデオキシヘモグロビンにおけるO2経路と脱出経路

Maria S Shadrina1, Ann M English, Gilles H Peslherbe

  • 1Department of Chemistry and Biochemistry and Centre for Research in Molecular Modeling, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec, Canada H4B 1R6.

Journal of the American Chemical Society
|June 14, 2012
PubMed
まとめ

私たちは,新しいシミュレーション方法を用いて,成人ヒトのヘモグロビンにおける酸素拡散を研究しました. 私たちの発見は,明確な拡散経路と複数の脱出経路を明らかにし,リガンドの移動に関する現在の仮説に挑戦しています.

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Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

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