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ATFS-1のミトコンドリア輸入効率は,ミトコンドリアのUPR活性化を調節する

Amrita M Nargund1, Mark W Pellegrino, Christopher J Fiorese

  • 1Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Science (New York, N.Y.)
|June 16, 2012
PubMed
まとめ

細胞は,ATFS-1タンパク質のミトコンドリアへの輸入を調節することによって,ミトコンドリアのストレスを感知します. 輸入量の減少により,ATFS-1が核に信号を送り,保護反応を活性化させることができます.

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