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減量外科手術前のおよび後のアルコール使用障害の発生率

Wendy C King¹, Jia-Yuh Chen, James E Mitchell

¹Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. kingw@edc.pitt.edu

|June 20, 2012

まとめ

腹腔外科手術はすぐにアルコール使用障害 (AUD) のリスクを増加させなかったが,流行率は2年目までに上昇した. 男性の性別,若い年齢,および手術前の特定の要因は,手術後のAUDリスクの上昇を予測します.

科学分野:

減量手術の結果について
依存症医学薬物中毒医学
胃腸内科胃腸内科

背景:

逸話的な証拠は,減量手術がアルコール使用障害 (AUD) のリスクを高めることを示唆しています.
減量外科手術後のAUDの流行に関する将来的なデータは限られている.

研究の目的:

減量外科手術前のおよび後のAUDの有病率を評価する.
術後のAUDの予測要因を特定するために.

主な方法:

バリアトリック手術を受けた2458人の成人を対象とした前向きなコホート研究.
AUDの症状は,アルコールの使用障害識別テスト (AUDIT) を使用して,手術後1年および2年後に評価されました.

主要な成果:

AUDの症状の流行率は,手術前 (7.6%) と手術後1年 (7.3%) に似ていたが,第2年 (9.6%) までに有意に増加した.
術後のAUDの独立予測要因には,男性の性別,若い年齢,喫煙,定期的なアルコール摂取,以前のAUD,レクリエーション用薬物使用,より低い対人サポート,およびRoux-en-Y胃バイパスが含まれています.

結論:

AUDの罹患率は,減量手術後の2年目に上昇する.
男性の性別,年少,および特定の術前要因は,術後のAUDリスクの増加と関連しています.

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