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Updated: May 21, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
10:59

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

サイト固有のDICERおよびDROSHARNA製品は,DNA損傷反応を制御する

Sofia Francia1, Flavia Michelini, Alka Saxena

  • 1IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy.

Nature
|June 23, 2012
PubMed
まとめ

DICERおよびDROSHA酵素は,DDRNAと呼ばれる新しい小RNAを生成する. これらのDDRNAは,DNA損傷反応 (DDR) 経路の活性化に不可欠であり,DNA修復におけるノンコーディングRNAの新たな役割を明らかにしています.

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy08:31

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DNA Damage can Stall the Cell Cycle

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DNA Damage Can Stall the Cell Cycle02:36

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