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Updated: May 1, 2026

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
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ファージチューブリンは,非典型的なメカニズムで動的フィラメントを組み立て,宿主細胞内のウイルスDNAを中心にします

James A Kraemer1, Marcella L Erb, Christopher A Waddling

  • 1Department of Biochemistry and Biophysics and the Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|June 26, 2012
PubMed
まとめ

バクテリオファージは,チューブリン状のタンパク質であるPhuZを使用して,ファージDNAの位置づけに不可欠なフィラメントを形成します. このダイナミックなPhuZ配列は,真核微小管のスパインドルに類似して機能し,ウイルスの繁殖に不可欠です.

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