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Updated: May 11, 2026

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Tiki1は,Wntの裂け方-酸化と無活性化による頭部形成に必要である

Xinjun Zhang1, Jose Garcia Abreu, Chika Yokota

  • 1The F. M. Kirby Neurobiology Center, Boston Children's Hospital, Department of Neurology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|June 26, 2012
PubMed
まとめ

研究者らは,頭形成に不可欠なWnt固有のプロテアゼであるTiki1を発見した. Tiki1は,Wntタンパク質を分裂させ,受容体結合を防止し,胚の発達を制御することによって,Wnt信号伝達を無効化する.

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