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Updated: May 21, 2026

Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers

Published on: September 19, 2022

循環性ペプチドの腸内浸透性:共通の主要な脊髄モチーフが特定されました

Johannes G Beck1, Jayanta Chatterjee, Burkhardt Laufer

  • 1Institute for Advanced Study and Center for Integrated Protein Science at the Technische Universität München, Department Chemie, Lichtenbergstrasse 4, 85747 Garching, Germany.

Journal of the American Chemical Society
|June 29, 2012
PubMed
まとめ

研究者らは,2つのペプチド構造を特定し,Caco-2細胞の透過性が高い. N-メチル化パターンは,これらのペプチド療法薬の経口生物利用性を達成するための鍵です.

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