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Updated: May 20, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

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Tヘルパー2細胞系統へのコミットメントを制御するエピジェネティックサイレンシング経路

Rhys S Allan1, Elina Zueva, Florence Cammas

  • 1Institut Curie Research Center, 26 rue d’Ulm, 75248 Paris Cedex 05, France.

Nature
|July 6, 2012
PubMed
まとめ

SUV39H1H3K9me3HP1α経路は,Tヘルパー1 (TH1) 遺伝子を静止することによって,Tヘルパー2 (TH2) 細胞の安定性を維持する. この経路の喪失はTH1反応を促進し,アレルギー性喘息を悪化させる.

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