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人間のCST複合体は,テロメラーゼの活性を終了するものである

Liuh-Yow Chen1, Sophie Redon, Joachim Lingner

  • 1Swiss Institute for Experimental Cancer Research (ISREC), Ecole Polytechnique Fédérale de Lausanne, Station 19, 1015 Lausanne, Switzerland.

Nature
|July 6, 2012
PubMed
まとめ

CST複合体 (CTC1,STN1,TEN1) は,拡張テロメアDNAに結合することでテロメアにおけるテロメラーゼの作用を制限する. このメカニズムは,細胞周期ごとに1つの延長イベントのみを許可することによって,テロメアの長さの調節を保証します.

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