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Updated: May 20, 2026

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
10:38

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

Published on: September 27, 2012

哺乳類の昼夜時計による転写終結のフィードバック調節 PERIOD 複合体

Kiran Padmanabhan1, Maria S Robles, Thomas Westerling

  • 1Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 7, 2012
PubMed
まとめ

哺乳類の昼夜時計は,PERIOD (PER) とCRYPTOCHROME (CRY) コンプレックスを使用して,転写を抑制する. これらのPER複合体は,直接的に転写終結を制御し,RNAポリメラーゼIIの放出と再起動を阻害する.

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