Lem4によるキナーゼとフォスファタゼの活動の調整により,ミトーシス中に核膜の再組み立てが可能になります

Claudio Asencio1, Iain F Davidson, Rachel Santarella-Mellwig

  • 1European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Cell
|July 10, 2012
PubMed
まとめ

核封筒のリフォームには,タンパク質BAFの脱酸化が必要です. 保存されたタンパク質Lem4/LEM-4Lは,キナーゼを阻害し,フォスファターゼと相互作用することによって,このプロセスを調節し,適切な細胞分裂を保証します.

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