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Updated: May 20, 2026

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テロメア重複を含むRNAがテロメアタンパク質TRF2に結合するには,分子内G四重複構造が必要である

Giulia Biffi1, David Tannahill, Shankar Balasubramanian

  • 1Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, UK.

Journal of the American Chemical Society
|July 12, 2012
PubMed
まとめ

テロメアタンパク質TRF2は,単に配列だけでなく,そのG四重複構造を通してテロメア重複を含むRNA (TERRA) を結合する. この結合は,テロメアへのTERRA局所化に不可欠であり,テロメアの組織に影響を与えます.

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