関連する実験動画

Updated: May 20, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

GPCRsのナトリウムイオンによるアロステリック調節の構造的基礎

Wei Liu1, Eugene Chun, Aaron A Thompson

  • 1Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|July 17, 2012
PubMed
まとめ

Gタンパク質結合受容体 (GPCR) の高解像度構造は,受容体機能における水,ナトリウムイオン,脂質の重要な役割を明らかにしています. この研究は,アデノシンA2A受容体の安定した構造を詳細に説明し,GPCR調節に関する新しい洞察を提供します.

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