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Updated: Apr 29, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 18, 2010

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形状エントロピーによるタンパク質活性調節.

Shiou-Ru Tzeng1, Charalampos G Kalodimos

  • 1Department of Chemistry & Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, USA.

Nature
|July 18, 2012
PubMed
まとめ

タンパク質のダイナミクスは,構造だけでなく,機能を決定します. 形状エントロピーと内部運動の変化は,タンパク質-リガンドの相互作用を調節し,カタボライト活性化タンパク質の変種におけるDNA結合親和性に影響を与えます.

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