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Updated: May 20, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

メドゥロブラストーマのエクソームシーケンシングにより,サブタイプに特異的な体的変異が発見されます

Trevor J Pugh1, Shyamal Dilhan Weeraratne, Tenley C Archer

  • 1Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature
|July 24, 2012
PubMed
まとめ

この研究は,一般的な脳腫瘍である小児性髄芽細胞腫における新しい遺伝子変異を特定しています. 発見にはDDX3XおよびN-CoR複合遺伝子の変異が含まれ,新しい治療標的を提供している.

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