関連する実験動画
Updated: May 20, 2026

09:34
Assessing Differences in Sperm Competitive Ability in Drosophila
Published on: August 22, 2013
性別特異的適応は,ドロソフィラの早期性染色体進化を駆動する
1Department of Integrative Biology, University of California Berkeley, Berkeley, CA 94720, USA.
まとめ
ドロソフィラ・ミランダの若いネオY染色体は,急速な変性および男性化を示しています. ネオY染色体の遺伝子は,より速く進化し,より古いX染色体とは異なり,男性組織に偏っている.
科学分野:
- 進化遺伝学の進化遺伝学について
- ゲノミクスゲノミクスとは
- 性染色体の進化について
背景:
- 性染色体はオートソームから進化するが,しばしばその起源のサインを失っている.
- Drosophila miranda neo-Y染色体は,約100万年前に発生した若いシステムです.
研究 の 目的:
- ドロソフィラ・ミランダの若いネオY染色体とネオX染色体におけるゲノムとトランスクリプトミックの変化を調査する.
- 最近進化した性染色体の遺伝子内容と発現を形作る進化的圧力を理解する.
主な方法:
- 全ゲノムシーケンシング
- トランスクリプトーム分析
- 比較ゲノミクスとは
主要な成果:
- ネオ-Y染色体は,大規模な遺伝子変性を示しています.
- neo-Yの男性に有益な遺伝子は,加速されたタンパク質の進化と男性組織に対する偏った発現を示し,男性化につながります.
- Neo-X遺伝子は男性組織で発現し,男性ではハプロイドで発現すると,タンパク質の進化も増加します.
結論:
- 性別特異的選択は,差異化過程で性染色体の遺伝子含有量の男性化と非男性化の両方を駆動することができます.
- 性染色体の進化の軌道はダイナミックで,その年齢と発現パターンに左右される.
関連する概念動画
The Ratio of X Chromosome to Autosomes
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
The Y Chromosome Determines Maleness
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Dosage Compensation
In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with distinct numbers of X chromosomes will have...
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with distinct numbers of X chromosomes will have...
X and Y Chromosomes
Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
Development of the Sexual Organs in the Embryo and Fetus
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...

