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Updated: May 20, 2026

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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Aβ集積に対する活性が強化されたヘテロディヴァラントリンクされたマクロサイクリックβシート: 2つのサイトは1つよりも優れている

Pin-Nan Cheng1, Ryan Spencer, R Jeremy Woods

  • 1Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, USA.

Journal of the American Chemical Society
|July 26, 2012
PubMed
まとめ

新しい異変性マクロサイクリックペプチドは,単価または同等性バージョンと比較して,アミロイドベータ (Aβ) アグリゲーションを抑制する活性が著しく向上しています. これらの化合物は,アミロイド系疾患を標的とした有望な戦略を提供します.

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