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Updated: May 19, 2026

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes
10:10

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes

Published on: July 28, 2018

Fe (III) /NaBH4媒介による非活性アルケンのフリーラディカルのフッ化水素化

Timothy J Barker1, Dale L Boger

  • 1Department of Chemistry and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|August 7, 2012
PubMed
まとめ

新しい鉄触媒反応により,Selectfluorを用いたアルケンの軽度かつ効率的なフリーラジカルによる水素フッ化が可能になる. この方法は,アクセシブルな条件下でマルコヴニコフ専用添加法を提供しており,従来のアプローチの限界を克服しています.

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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

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