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HSF1は熱ショックとは異なるトランスクリプションプログラムを駆動し,高悪性ヒトがんをサポートします

Marc L Mendillo1, Sandro Santagata, Martina Koeva

  • 1The Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Cell
|August 7, 2012
PubMed
まとめ

熱ショック因子1 (HSF1) は,熱ショックタンパク質を超えた遺伝子を独特に調節することによって癌を誘発する. このHSF1がんプログラムは,腫瘍に活性化し,転移と患者の死亡に関連しています.

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