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Updated: May 19, 2026

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Parp1とTet2による体細胞再プログラム中の初期段階の表遺伝的変化

Claudia A Doege1, Keiichi Inoue, Toru Yamashita

  • 1Department of Pathology, Taub Institute for Aging, Columbia University, New York, New York 10032, USA.

Nature
|August 21, 2012
PubMed
まとめ

ポリ ((ADP-リボース) ポリメラーゼ-1 (Parp1) と10−11トランスロケーション-2 (Tet2) は,誘発性多能幹細胞 (iPSC) 再プログラム中の早期の表遺伝的変化に不可欠である. これらの要因は,異なった表遺伝子記号を確立し,多能性遺伝子の活性化を促します.

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