内生抗原は,ナイブなB細胞の反応を調節するが,T細胞の反応は調節しない

Julie Zikherman1, Ramya Parameswaran, Arthur Weiss

  • 1Division of Rheumatology, Department of Medicine, Rosalind Russell Medical Research Center for Arthritis, University of California, San Francisco, California 94143, USA.

Nature
|August 21, 2012
PubMed
まとめ

自発反応性B細胞は成熟したレパートリーに存在し,機能的反応不全またはアナージーによって耐性を確立します. B細胞の発達中の抗原曝露は,B細胞受容体のシグナル伝達反応を調節する.

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