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Updated: May 19, 2026

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
07:34

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

Published on: December 16, 2021

腸内炎症は,微生物群のがん誘発活性を標的とする

Janelle C Arthur1, Ernesto Perez-Chanona, Marcus Mühlbauer

  • 1Department of Medicine, Pharmacology and Immunology-Microbiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|August 21, 2012
PubMed
まとめ

炎症は腸内微生物を変化させることで結腸直腸がん (CRC) を促進する. 遺伝子毒性の島を運ぶ特定の細菌である大腸菌 (Escherichia coli) は,感受性の高いマウスの腫瘍増殖を促し,CRCの予防のための微生物標的を強調しています.

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