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Updated: May 19, 2026

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
10:52

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation

Published on: January 6, 2016

フォスフォフルトキナーゼ1のグリコシル化により,細胞の成長と代謝が調節されます

Wen Yi1, Peter M Clark, Daniel E Mason

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

Science (New York, N.Y.)
|August 28, 2012
PubMed
まとめ

癌細胞はO-リンクされたβ-N-アセチルグルコサミン (O-GlcNAcylation) を利用して,成長のためのグルコース代謝を変化させます. リン酸フルークトキナーゼ1 (PFK1) のこの改変を阻害すると,癌細胞の増殖と腫瘍形成が妨げられます.

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Oligopeptide Competition Assay for Phosphorylation Site Determination

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