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漏れのある神経ライオノジン受容体の役割 ストレス誘発の認知機能不全

Xiaoping Liu1, Matthew J Betzenhauser, Steve Reiken

  • 1Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

Cell
|September 4, 2012
PubMed
まとめ

慢性的なストレスは,脳のRyR2チャネルの機能不全を引き起こし,記憶と学習を損なう. これらのチャネルをS107または遺伝子組み換えで安定させると,認知機能が回復し,RyR2が治療目標であると示唆される.

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